Family

Trafficking protein particle complex subunit (IPR007233)

Short name: TRAPPC

Family relationships

None.

Description

This entry includes a group of trafficking protein particle complex subunit (TRAPPC) proteins, such as TPPC1/4 from humans and Trs23/Bet5 from yeasts.

Budding yeast Trs23 and Bet5 are components of the TRAPP I, TRAPP II and TRAPP III. TRAPP complexes are guanine nucleotide exchange factors (GEF) for the GTPase Ypt1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. RAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation [PMID: 11239471, PMID: 20972447, PMID: 20375281].

GO terms

Biological Process

GO:0006810 transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0030008 TRAPP complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam
PANTHER