TolB, N-terminal (IPR007195)

Short name: TolB_N

Overlapping homologous superfamilies

Domain relationships



TolB is a periplasmic protein from Escherichia coli that is part of the Tol-dependent translocation system involving group A and E colicins that is used to penetrate and kill cells [PMID: 10545334, PMID: 10673426]. TolB has two domains, an alpha-helical N-terminal domain that shares structural similarity with the C-terminal domain of transfer RNA ligases, and a beta-propeller C-terminal domain (IPR011042) that shares structural similarity with numerous members of the prolyl oligopeptidase family and, to a lesser extent, to class B metallo-beta-lactamases [PMID: 10545334]. The function of the N-terminal domain is uncertain.

GO terms

Biological Process

GO:0015031 protein transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0042597 periplasmic space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.