Transport protein particle (TRAPP) component (IPR007194)

Short name: TRAPP_component

Overlapping homologous superfamilies

Family relationships


TRAPP plays a key role in the targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment. TRAPP is a large multimeric protein that contains at least 10 subunits. This family contains many TRAPP family proteins. The Bet3 subunit is one of the better characterised TRAPP proteins and has a dimeric structure [PMID: 15608655] with hydrophobic channels. The channel entrances are located on a putative membrane-interacting surface that is distinctively flat, wide and decorated with positively charged residues. Bet3 is proposed to localise TRAPP to the Golgi [PMID: 9564032].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.