Ferrous iron transporter FeoA domain (IPR007167)

Short name: Fe-transptr_FeoA

Overlapping homologous superfamilies

Domain relationships



This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C terminus in related proteins. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.

The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor [PMID: 8407793, PMID: 16718600]. Feo allows the bacterial cell to acquire iron from its environment.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0046914 transition metal ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.