Ribosome modulation factor (IPR007040)

Short name: Ribosome_modulation_factor

Overlapping homologous superfamilies

Family relationships



This entry contains ribosome modulation factors (RMF). They associate with 70s ribosomes and converts them to a dimeric form (100S ribosomes) which appear during the transition from the exponential growth phase to the stationary phase of Escherichia colicells [PMID: 8440252, PMID: 2181444].

It has been proposed that RMF mediates the formation of a 'storage ribosome', the 100S particle, in stationary phase by inactivating excess ribosomes to protect them from degradation and to maintain the required balance between the concentrations of ribosomes and protein synthesis factors in order to maintain translational elongation efficiency [PMID: 16088400, PMID: 17185553].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.