Family

Succinylglutamate desuccinylase/aspartoacylase (IPR007036)

Short name: Aste_AspA

Family relationships

Description

This family describes both succinylglutamate desuccinylase that catalyses the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway and also includes aspartoacylase EC:3.5.1.15 which cleaves acylaspartate into a fatty acid and aspartate. Mutations in P45381 lead to Canavan disease [PMID: 8252036].

GO terms

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0016788 hydrolase activity, acting on ester bonds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF