Family

Succinylglutamate desuccinylase/aspartoacylase (IPR007036)

Short name: Aste_AspA

Overlapping homologous superfamilies

None.

Family relationships

Description

This family describes both succinylglutamate desuccinylase that catalyses the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway and also includes aspartoacylase EC:3.5.1.15 which cleaves acylaspartate into a fatty acid and aspartate. Mutations in P45381 lead to Canavan disease [PMID: 8252036].

GO terms

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0016788 hydrolase activity, acting on ester bonds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF