BLUF domain (IPR007024)

Short name: BLUF_domain

Overlapping homologous superfamilies

Domain relationships



The BLUF domain (named for sensors of Blue-Light Using FAD) is an FAD-binding protein domain. BLUF domains are present in various proteins, primarily from bacteria. For example a BLUF domain is found at the N terminus of the AppA protein from Rhodobacter sphaeroides [PMID: 16323221]. BLUF domains are involved in sensing blue-light (and possibly redox) using FAD, and are similar to the flavin-binding PAS domains and cryptochromes. Their predicted secondary structure reveals that the BLUF domains have a novel FAD-binding fold [PMID: 12368079].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0071949 FAD binding
GO:0009882 blue light photoreceptor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles