Domain

NAB co-repressor, domain (IPR006989)

Short name: NAB_co-repressor_dom

Domain relationships

None.

Description

Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors [PMID: 9418898]. This entry represents a NAB domain near the C terminus of the protein. It is necessary for transcriptional repression by the Nab proteins [PMID: 9418898]. It is also required for transcription activation by Nab proteins at Nab-activated promoters [PMID: 10734128].

GO terms

Biological Process

GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam