Domain

Nab, N-terminal (IPR006988)

Short name: Nab_N

Domain relationships

None.

Description

Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors [PMID: 9418898]. This entry represents the N-terminal NAB domain, which interacts with the EGR1 inhibitory domain (R1) [PMID: 9418898]. It may also mediate multimerisation.

GO terms

Biological Process

GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom