Popeye protein (IPR006916)

Short name: Popeye_prot

Overlapping homologous superfamilies


Family relationships



The Popeye (POP) family of proteins, is mainly restricted to vertebrates and is preferentially expressed in developing and adult striated muscle. It is represented by a conserved region which includes three potential transmembrane domains [PMID: 10882522]. The strong conservation of POP genes during evolution and their preferential expression in heart and skeletal muscle suggest that these novel proteins may have an important function in these tissues in vertebrates.

A number of uncharacterized protein homologues are known from bacteria, invertebrates and apicomplexan protozoa.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.