DNA-directed RNA polymerase III subunit Rpc5 (IPR006886)

Short name: RNA_pol_III_Rpc5

Overlapping homologous superfamilies


Family relationships



DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. RNA polymerase III (Pol III) is a complex consisting of 17 subunits, which synthesizes small RNAs, such as 5S rRNA and tRNAs. Pol III is essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters and plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Subunit c5 is a specific peripheric component of RNA polymerase III complex.

GO terms

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003899 DNA-directed 5'-3' RNA polymerase activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.