Family

Glycosyl transferase, family 17 (IPR006813)

Short name: Glyco_trans_17

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family represents beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (EC:2.4.1.144). This enzyme transfers the bisecting GlcNAc to the core mannose of complex N-glycans. The addition of this residue is regulated during development and has functional consequences for receptor signalling, cell adhesion, and tumour progression [PMID: 11986323, PMID: 11784313].

GO terms

Biological Process

GO:0006487 protein N-linked glycosylation

Molecular Function

GO:0003830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER