TAFII28-like protein (IPR006809)

Short name: TAFII28

Overlapping homologous superfamilies

Domain relationships



The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcription preinitiation complex. The conserved region is found at the C terminus of most member proteins. The crystal structure of hTAFII28 with hTAFII18 shows that this region is involved in the binding of these two subunits. The conserved region contains four alpha helices and three loops arranged as in histone H3 [PMID: 7729427, PMID: 9695952].

GO terms

Biological Process

GO:0006367 transcription initiation from RNA polymerase II promoter

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.