Family

Pellino family (IPR006800)

Short name: Pellino_fam

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Pellino proteins are E3 ubiquitin ligases that play an important role in immunity [PMID: 26085209, PMID: 24445667]. Pellinos contain a CHC2CHC2 RING E3 ubiquitin ligase domain [PMID: 16884718]. Mammalian Pellinos have been shown to mediate polyubiquitination of interleukin-1 receptor-associated kinase (IRAK) [PMID: 16884718, PMID: 19022706].

GO terms

Biological Process

GO:0000209 protein polyubiquitination
GO:0008592 regulation of Toll signaling pathway

Molecular Function

GO:0061630 ubiquitin protein ligase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
PIRSF
Pfam