Family

Pellino family (IPR006800)

Short name: Pellino_fam

Family relationships

None.

Description

Pellino proteins have been suggested to function as evolutionary conserved scaffold proteins in Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signalling [PMID: 17635639]. Pellinos contain a CHC2CHC2 RING E3 ubiquitin ligase domain [PMID: 16884718]. Mammalian Pellinos have been shown to mediate polyubiquitination of interleukin-1 receptor-associated kinase (IRAK) [PMID: 16884718, PMID: 19022706].

GO terms

Biological Process

GO:0008063 Toll signaling pathway

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
Pfam
PANTHER