Domain

Dickkopf, N-terminal cysteine-rich (IPR006796)

Short name: Dickkopf_N

Domain relationships

None.

Description

Dickkopf proteins are a class of Wnt antagonists. They possess two conserved cysteine-rich regions. This entry represents the N-terminal conserved region [PMID: 12167704]. The C-terminal region has been found to share significant sequence similarity to the colipase fold (IPR001981) [PMID: 9663378].

GO terms

Biological Process

GO:0007275 multicellular organism development
GO:0030178 negative regulation of Wnt signaling pathway

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam