Domain

Transcriptional activator, Zfx / Zfy domain (IPR006794)

Short name: Transcrp_activ_Zfx/Zfy-dom

Domain relationships

None.

Description

Zfx and Zfy are transcription factors implicated in mammalian sex determination. This region is found N-terminal to multiple copies of a C2H2 Zinc finger. This region has been shown to activate transcription when fused to a GAL4 DNA binding domain [PMID: 2105457].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0046872 metal ion binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam