Domain

Peroxisome membrane anchor protein Pex14p, N-terminal (IPR006785)

Short name: Pex14_N

Domain relationships

None.

Description

This conserved region defines a group of peroxisomal membrane anchor proteins which bind the PTS1 (peroxisomal targeting signal) receptor and are required for the import of PTS1-containing proteins into peroxisomes. Loss of functional Pex14p results in defects in both the PTS1 and PTS2-dependent import pathways. Deletion analysis of this conserved region implicates it in selective peroxisome degradation. In the majority of members this region is situated at the N terminus of the protein [PMID: 9094717, PMID: 11564741].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam