Domain

Calcium uniporter protein, C-terminal (IPR006769)

Short name: MCU_C

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the C-terminal domain of MCU, which is a mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria [PMID: 21685888, PMID: 21685886, PMID: 23101630]. This domain can also be found in MCUb, which negatively regulates the activity of MCU [PMID: 23900286].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam