Domain

PEA3-type ETS-domain transcription factor, N-terminal (IPR006715)

Short name: ETS_PEA3_N

Domain relationships

None.

Description

The N-terminal of the PEA3 transcription factors is implicated in transactivation and in inhibition of DNA binding [PMID: 9259977]. Transactivation is potentiated by activation of the Ras/MAP kinase and protein kinase A signalling cascades. The N-terminal region contains conserved MAP kinase phosphorylation sites [PMID: 9285689].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003700 sequence-specific DNA binding transcription factor activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam