Fatty acid hydroxylase (IPR006694)

Short name: Fatty_acid_hydroxylase

Overlapping homologous superfamilies


Domain relationships



This superfamily includes fatty acid and carotene hydroxylases and sterol desaturases. Beta-carotene hydroxylase is involved in zeaxanthin synthesis by hydroxylating beta-carotene, but the enzyme may be involved in other pathways [PMID: 8718622]. This family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis a plant cuticular wax. These enzymes contain two copies of a HXHH motif. Members of this family are integral membrane proteins.

GO terms

Biological Process

GO:0008610 lipid biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.