Repeat

DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (IPR006691)

Short name: GyrA/parC_rep

Description

This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure [PMID: 11948780]. This region has been shown to bind DNA non-specifically and may stabilise the DNA-topoisomerase complex [PMID: 1657531].

GO terms

Biological Process

GO:0006265 DNA topological change

Molecular Function

GO:0005524 ATP binding
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity

Cellular Component

GO:0005694 chromosome

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam