Family

Splicing factor ELAV/Hu (IPR006548)

Short name: ELAD_HU_SF

Family relationships

Description

These sequences represent the ELAV/Hu subfamily of splicing factors found in metazoa. ELAV stands for the Drosophila Embryonic lethal abnormalvisual protein [PMID: 3144044]. ELAV-like splicing factors are also known in human as HuB (ELAV-like protein 2), HuC (ELAV-like protein 3, HuD (LAV-like protein 4) and HuR (ELAV-like protein 1). HuR is ubiquitously expressed whereas HuB, HuC and HuD are neuron-specific [PMID: 22139917]. HuD stands for the human paraneoplastic encephalomyelitis antigen D of which there are 4 variants in human [PMID: 1655278]. These genes are most closely related to the sex-lethal subfamily of splicing factors found in Dipteran insects (IPR006546).

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003723 RNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs