Splicing factor, RBM39-like (IPR006509)

Short name: RBM39_SF

Overlapping homologous superfamilies


Family relationships



This entry represents RBM39 (also known as CAPER) proteins from mammals and a group of putative RNA splicing factors including the Pad1 protein from fungi. All are characterised by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 human paralogs, two) RNA recognition domains. These proteins are closely related to the U2AF splicing factor family (IPR006529).

In mice, CAPER is a transcriptional coactivator of activating protein-1 (AP-1) and estrogen receptors (ERs) [PMID: 11704680]. It may be involved in pre-mRNA splicing process.

GO terms

Biological Process

GO:0006397 mRNA processing

Molecular Function

GO:0003723 RNA binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.