Formate dehydrogenase iron-sulphur subunit, Proteobacteria (IPR006470)

Short name: Formate_DH_bsu_Proteobacteria

Overlapping homologous superfamilies


Family relationships


The sequences in this group represent the beta subunit of the gamma-proteobacterial formate dehydrogenase. This subunit contains four 4Fe-4S clusters and is involved in transmitting electrons from the alpha subunit (IPR006443) at the periplasmic space to the gamma subunit which spans the cytoplasmic membrane [PMID: 11884747]. In addition to the gamma proteobacteria, a sequence from Aquifex aolicus falls within this group. This appears to be the case for the alpha, gamma and epsilon (accessory protein IPR006452) chains as well.

GO terms

Biological Process

GO:0045333 cellular respiration
GO:0015944 formate oxidation

Molecular Function

GO:0051539 4 iron, 4 sulfur cluster binding

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.