Family

MiaB-like tRNA modifying enzyme, archaeal-type (IPR006466)

Short name: MiaB-like_B

Overlapping homologous superfamilies

Family relationships

Description

This clade of sequences is closely related to MiaB, a modifier of isopentenylated adenosine-37 of certain eukaryotic and bacterial tRNAs (see IPR006463). Sequence alignments suggest that this family of sequences perform the same chemical transformation as MiaB, perhaps on a different (or differently modified) tRNA base substrate. This clade represents a subfamily that spans the archaea and eukaryotes. The only archaeal miaB-like genes are in this group of sequences [PMID: 10572129, PMID: 11882645, PMID: 11313137].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs