HAD-superfamily hydrolase, subfamily IF, YfhB (IPR006435)

Short name: HAD-SF_hydro_IF_YfhB

Overlapping homologous superfamilies

Family relationships



This group describes a clade of sequences limited to the gamma proteobacteria. This group is a member of the haloacid dehalogenase (HAD) superfamily of aspartate-dependent hydrolases and all of the conserved catalytic motifs are present [PMID: 7966317]. Although structurally similar to subfamily IA in that the variable domain is predicted to consist of five consecutive alpha helices (by PSI-PRED), it is sufficiently divergent to warrant being regarded as a separate sub-family (IF).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.