5-nucleotidase lipoprotein e(P4) (IPR006423)

Short name: Lipo_e_P4

Overlapping homologous superfamilies

Family relationships


This entry represents a set of bacterial lipoproteins belonging to a larger acid phosphatase family (IPR005519), which in turn belongs to the haloacid dehalogenase (HAD) superfamily of aspartate-dependent hydrolases. Members are found on the outer membrane of Gram-negative bacteria and the cytoplasmic membrane of Gram-positive bacteria. Most members have classic lipoprotein signal sequences. A critical role of this 5'-nucleotidase in Haemophilus influenzae is the degradation of external riboside in order to allow transport into the cell. An earlier suggested role in hemin transport is no longer current. This enzyme may also have other physiologically significant roles [PMID: 11395461].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0009279 cell outer membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.