Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype (IPR006411)

Short name: Fruct_bisP_bact

Overlapping homologous superfamilies

Family relationships


Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). They represent one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterised proteins. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures [PMID: 1412694]. This family is well-conserved and includes characterised FBA from Saccharomyces cerevisiae (Baker's yeast),Escherichia coli, and Corynebacterium glutamicum.

GO terms

Biological Process

GO:0006096 glycolytic process

Molecular Function

GO:0004332 fructose-bisphosphate aldolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.