Nicotinate phosphoribosyltransferase (IPR006406)

Short name: Nic_PRibTrfase

Overlapping homologous superfamilies

Family relationships


This family represents nicotinate phosphoribosyltransferase, the first enzyme in the salvage pathway of NAD biosynthesis from nicontinate (niacin). Members are primarily proteobacterial but also include yeasts and Methanosarcina acetivorans. A related family, apparently non-overlapping in species distribution, is IPR006405. Members of that family differ in substantially in sequence and have a long C-terminal extension missing from this family, but are proposed also to act as nicotinate phosphoribosyltransferase.

GO terms

Biological Process

GO:0019357 nicotinate nucleotide biosynthetic process

Molecular Function

GO:0004516 nicotinate phosphoribosyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.