HAD-superfamily hydrolase, superfamily IIB, MPGP (IPR006381)

Short name: HAD-SF-IIB-MPGP

Overlapping homologous superfamilies

Family relationships


This group of proteins is a member of the IIB subfamily of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. It consists of mannosyl-3-phosphoglycerate phosphatase from Pyrococcus horikoshii [PMID: 11562374] and related proteins, including GpgP from Methanococcoides burtonii and Persephonella marina, which can catalyse the dephosphorylation of both glucosyl-3-phosphoglycerate and mannosyl-3-phosphoglycerate [PMID: 16428406, PMID: 17189358].

GO terms

Biological Process

GO:0051479 mannosylglycerate biosynthetic process

Molecular Function

GO:0050531 mannosyl-3-phosphoglycerate phosphatase activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.