Sucrose-phosphatase-like, N-terminal (IPR006380)

Short name: SPP_N

Domain relationships


This entry represents a conserved region of the sucrose phosphate phosphohydrolase (SPP) from plants and cyanobacteria [PMID: 11050182]. SPP is a member of the Class IIB subfamily of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. SPP catalyzes the final step in the biosynthesis of sucrose, a critically important molecule for plants. Sucrose phosphate synthase (SPS), the prior step in the biosynthesis of sucrose contains a domain which exhibits considerable similarity to SPP albeit without conservation of the catalytic residues. The catalytic machinery of the synthase resides in another domain. It seems likely that the phosphatase-like domain is involved in substrate binding, possibly binding both substrates in a "product-like" orientation prior to ligation by the synthase catalytic domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.