Methyltransferase FkbM (IPR006342)

Short name: FkbM_mtfrase

Overlapping homologous superfamilies

Domain relationships



This domain is characterised by two well-conserved short regions separated by a variable region in both sequence and length. The first of the two regions is found in a large number of proteins outside this group, a number of which have been characterised as methyltransferases. One member of this group, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548 [PMID: 8752344].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.