Family

AMP deaminase (IPR006329)

Short name: AMPD

Family relationships

Description

AMP-deaminase (AMPD) is a large, well-conserved eukaryotic protein that catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) to inosine monophosphate (IMP), and so plays an important role in purine metabolism. In mammalian liver, the reaction catalysed by AMP-deaminase constitutes a rate-limiting step in adenine nucleotide catabolism [PMID: 18493842].

GO terms

Biological Process

GO:0032264 IMP salvage

Molecular Function

GO:0003876 AMP deaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
PANTHER
PIRSF
TIGRFAMs