L-2-Haloacid dehalogenase (IPR006328)

Short name: 2-HAD

Overlapping homologous superfamilies

Family relationships



These proteins catalyze the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids [PMID: 11404103]. They belong to the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases, class (subfamily) I. Note that the Type I HAD enzymes have not yet been fully characterised, but clearly utilise a substantially different catalytic mechanism and are thus unlikely to be related.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0019120 hydrolase activity, acting on acid halide bonds, in C-halide compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.