Domain

Phosphotransferase system, enzyme I-like (IPR006318)

Short name: PTS_EI-like

Domain relationships

None.

Description

Most proteins with this domain are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferases (or enzyme I) of PTS sugar transport systems. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). This domain is also found in enzyme I-Ntr, which transfers the phosphoryl group from PEP to the phosphoryl carrier protein NPr, and is involved in regulating nitrogen metabolism [PMID: 18421563], indicating that not all phosphotransferase system components are associated directly with sugar transport. In Xanthomonas campestris, FruB is a multiphosphoryl transfer protein involved in fructose transport that consists of three domains: a fructose-specific enzyme-IIA-like N-terminal domain, followed by an HPr-like domain and an enzyme-I-like C-terminal domain, represented by this entry [PMID: 7496537].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016772 transferase activity, transferring phosphorus-containing groups

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs