Family

Glutathione synthetase, prokaryotic (IPR006284)

Short name: Glut_synth_pro

Family relationships

None.

Description

These are the glutathione synthetases found in Gram-negative bacteria. This gene does not appear to be present in genomes of Gram-positive bacteria. Glutathione synthetase has an ATP-binding domain in the COOH terminus and catalyzes the second step in the glutathione biosynthesis pathway: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. Glutathione is a tripeptide that functions as a reductant in many cellular reactions.

GO terms

Biological Process

GO:0006750 glutathione biosynthetic process

Molecular Function

GO:0004363 glutathione synthase activity

Cellular Component

GO:0005829 cytosol

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
HAMAP
TIGRFAMs