Dihydrolipoamide succinyltransferase (IPR006255)

Short name: SucB

Overlapping homologous superfamilies

Family relationships



These sequences describe the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. Members include the mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N terminus and are generally excluded from this group of sequences as are all examples of dihydrolipoamide acetyltransferase.

GO terms

Biological Process

GO:0006099 tricarboxylic acid cycle

Molecular Function

GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity

Cellular Component

GO:0045252 oxoglutarate dehydrogenase complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.