InterPro

This entry represents the anthranilate synthase/para-aminobenzoate synthase domain, which share sequence similarity to the glutamine amidotransferase domain IPR017926. Anthranilate synthase play a role in the tryptophan-biosynthetic pathway, while the para-aminobenzoate synthase is involved in the folate biosynthetic pathway. In at least one case, a single polypeptide from Bacillus subtilis was shown to have both functions. Proteins containing this domain include anthranilate synthase, anthranilate synthase component II, para-aminobenzoate synthase and aminodeoxychorismate synthase.