Conserved Site

Bax inhibitor 1, conserved site (IPR006213)

Short name: Bax_inhbtr1_CS

Description

Bax inhibitor-1 (BI-1) (gene TEGT) [PMID: 8530040] is a suppressor of apoptosis that interacts with BCL2 and BCL-X. These are proteins of about 25 kDa which seem to contain seven transmembrane domains. Homologues are found in plants and bacteria.

This entry corresponds to a conserved region that starts with the beginning of the third transmembrane domain and ends in the middle of the fourth one.

GO terms

Biological Process

GO:0043066 negative regulation of apoptotic process

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns