Mevalonate kinase (IPR006205)

Short name: Mev_gal_kin

Overlapping homologous superfamilies

Family relationships


Mevalonate kinase (EC: is well-characterised among the Eukaryotes, where it plays a role in the synthesis of isopentanyl pyrophosphate, a common intermediate for a number of pathways including cholesterol biosynthesis. It is also involved in mevalonate catabolism. Close homologues are found in the Archaea. A bacterial example is found in the Borrelia burgdorferi (Lyme disease spirochete), but is not necessarily the same biosynthetic enzyme.

GO terms

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

GO:0005524 ATP binding
GO:0004496 mevalonate kinase activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.