Domain

GHMP kinase N-terminal domain (IPR006204)

Short name: GHMP_kinase_N_dom

Domain relationships

None.

Description

The galacto- (EC:2.7.1.6), homoserine (EC:2.7.1.39), mevalonate (EC:2.7.1.36) and phosphomevalonate (EC:2.7.4.2) kinases contain, in their N-terminal section, a conserved domain with a Gly/Ser-rich region which is probably involved in the binding of ATP [PMID: 1846667, PMID: 10562426]. This group of kinases has been called 'GHMP' (from the first letter of their substrates).

This domain is also found in diphosphomevalonate decarboxylases, which are structurally related members of the GHMP superfamily [PMID: 17583736], but do not possess kinase activity.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005524 ATP binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam