Conserved Site

GHMP kinase, ATP-binding, conserved site (IPR006203)

Short name: GHMP_knse_ATP-bd_CS

Description

The galacto- (EC:2.7.1.6), homoserine (EC:2.7.1.39), mevalonate (EC:2.7.1.36) and phosphomevalonate (EC:2.7.4.2) kinases contain, in their N-terminal section, a conserved Gly/Ser-rich region which is probably involved in the binding of ATP [PMID: 1846667, PMID: 10562426]. This group of kinases has been called 'GHMP' (from the first letter of their substrates).

This site is also found in some diphosphomevalonate decarboxylases, which are structurally related members of the GHMP superfamily [PMID: 17583736], but do not possess kinase activity.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005524 ATP binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns