Conserved Site

Secretion protein HlyD, conserved site (IPR006144)

Short name: Secretion_HlyD_CS


Gram-negative bacteria produce a number of proteins which are secreted into the growth medium by a mechanism that does not require a cleaved N-terminal signal sequence. These proteins, while having different functions, require the help of two or more proteins for their secretion across the cell envelope.

The secretion proteins are evolutionary related and consist of from 390 to 480 amino acid residues. They seem to be anchored in the inner membrane by a N-terminal transmembrane region. The C-terminal section of these proteins is the best conserved region.

GO terms

Biological Process

GO:0009306 protein secretion

Molecular Function

GO:0008565 protein transporter activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns