Family

Adhesion lipoprotein (IPR006128)

Short name: Lipoprotein_4

Family relationships

Description

The Streptococcus pneumoniae psaA gene encodes a protein with significant similarity to previously-reported Streptococcal proteins, SsaB (80% similarity) and FimA (92.3% similarity), from Streptococcus sanguis and Streptococcus parasanguis [PMID: 7505262]. These homologues are associated with bacterial adhesion, and PsaA may play a similar role [PMID: 7505262].

The SsaB protein has a putative hydrophobic 19-amino-acid signal sequence yielding a 32,620-Mr secreted protein [PMID: 1671775]. SsaB is hydrophilic and appears not to have a hydrophobic membrane anchor in its C-terminal region. A high degree of similarity exists between S. sanguis ssaB and type 1 fimbrial genes [PMID: 1671775]. Comparison of the gene products reveals close similarity of the two proteins. It is thought that ssaB adhesion may play a role in oral colonisation by binding either to a receptor on saliva or to a receptor on Actinomyces.

This family includes the adhesins and related periplasmic binding proteins.

GO terms

Biological Process

GO:0007155 cell adhesion

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS