Conserved Site

Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site (IPR006126)

Short name: Staph/Strept_toxin_CS


Staphylococcal enterotoxins and streptococcal pyrogenic exotoxins constitute a family of biologically and structurally related toxins produced by Staphylococcus aureus and Streptococcus pyogenes [PMID: 2679358, PMID: 2185544]. These toxins share the ability to bind to the major histocompatibility complex proteins of their hosts. A more distant relative of the family is the S. aureus toxic shock syndrome toxin (TSST-1), which shares only a low level of sequence similarity with this group.

This family is identified by a well conserved region of enterotoxins and pyrogenic exotoxins, but which does not pick up TSST-1.

GO terms

Biological Process

GO:0009405 pathogenesis

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns