Metalloenzyme (IPR006124)

Short name: Metalloenzyme

Overlapping homologous superfamilies

Domain relationships



This domain unites alkaline phosphatase, N-acetylgalactosamine-4-sulphatase, and cerebroside sulphatase, enzymes with known three-dimensional structures, with phosphopentomutase, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, phosphoglycerol transferase, phosphonate monoesterase, streptomycin-6-phosphate phosphatase, alkaline phosphodiesterase/nucleotide pyrophosphatase PC-1, and several closely related sulphatases. This domain is also related to alkaline phosphatase IPR001952 [PMID: 10082381]. The most conserved residues are probably involved in metal binding and catalysis.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003824 catalytic activity
GO:0046872 metal ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.