Glycerol kinase (IPR005999)

Short name: Glycerol_kin

Overlapping homologous superfamilies


Family relationships


Glycerol kinase (EC: is a bacterial sugar kinase which catalyzes the Mg-ATP-dependent phosphorylation of glycerol to yield glycerol 3-phosphate. The enzyme from Escherichia coli is an allosteric regulatory enzyme whose activity is inhibited by fructose 1,6-bisphosphate (FBP) and the glucose-specific phosphocarrier of the phosphoenolpyruvate:glycose phosphotransferase system, IIA(Glc), structural studies suggest a nucleophilic in-line transfer mechanism for the ATP-dependent phosphorylation of glycerol by glycerol kinase [PMID: 10364471].

GO terms

Biological Process

GO:0006072 glycerol-3-phosphate metabolic process

Molecular Function

GO:0004370 glycerol kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.