Phosphoglycerate mutase 1 (IPR005952)

Short name: Phosphogly_mut1

Overlapping homologous superfamilies

Family relationships


Most members of this family are phosphoglycerate mutase (EC: This enzyme interconverts 2-phosphoglycerate and 3-phosphoglycerate. 2-phospho-D-glycerate + 2,3-diphosphoglycerate = 3-phospho-D-glycerate + 2,3-diphosphoglycerate. The enzyme is transiently phosphorylated on an active site histidine by 2,3-diphosphoglyerate, which is both substrate and product. Some members of this family have are phosphoglycerate mutase as a minor activity and act primarily as a bisphoglycerate mutase, interconverting 2,3-diphosphoglycerate and 1,3-diphosphoglycerate (EC:

GO terms

Biological Process

GO:0006096 glycolytic process

Molecular Function

GO:0016868 intramolecular transferase activity, phosphotransferases
GO:0004619 phosphoglycerate mutase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.