Family

Higher eukaryotic phosphomevalonate kinase (IPR005919)

Short name: Pmev_kin_anim

Family relationships

None.

Description

Phosphomevalonate kinase (EC:2.7.4.2) catalyzes the phosphorylation of 5-phosphomevalonate into 5-diphosphomevalonate, an essential step in isoprenoid biosynthesis via the mevalonate pathway. In an example of nonorthologous gene displacement, two different types of phosphomevalonate kinase are found - the higher eukaryotic form and the ERG8 type. This model represents the form of the enzyme found in animals.

GO terms

Biological Process

GO:0006695 cholesterol biosynthetic process

Molecular Function

GO:0004631 phosphomevalonate kinase activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
Pfam
PANTHER
TIGRFAMs