Histidinol-phosphate aminotransferase family (IPR005861)

Short name: HisP_aminotrans

Overlapping homologous superfamilies

Family relationships


The histidinol phosphate aminotransferase family consists of class I pyridoxal-5'-phosphate (PLP)-dependent enzymes that catalyze a step of L-histidine biosynthesis [PMID: 8636014]. These proteins are highly specific enzymes in the sense that no other aminotransferases are known to be capable of utilizing imidazoleacetol phosphate, with deletions leading to auxotrophy. A subgroup of these enzymes have broader substrate specificity and are capable of using aromatic amino acid substrates in vitro and in vivo

GO terms

Biological Process

GO:0000105 histidine biosynthetic process

Molecular Function

GO:0004400 histidinol-phosphate transaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.